We've been very interesting in experimenting with the current Escape Room trend in VR. We want to use physical objects in a mix of real space and virtual space to create a unique experience that's only possible in VR (I was especially inspired after seeing the Arizona Sunshine demo at the Intel Skybridge at GDC.)
We've designed for physical interactive experience before, and our team has a lot of experience designing for VR. One interesting problem we've come across when thinking about this Escape Room idea is having the player walk through doorways/barriers. Being tethered to a computer makes this a frustrating design challenge, but by using the MSI VR One backpack, we could eliminate the problem completely!